Armed with estrogens, female cells are better poised to fight the flu

NIAID CEIRS | Research Publication Commentary Peretz, J, et al. Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors. Am J Physiol Lung Cell Mol Physiol. (2015). It seems that the playing field is not entirely even between the sexes when it comes to… Read more »

Conserved molecular signatures help predict immune responses to vaccination in the young and elderly

NIAID CEIRS | Research Publication Commentary Nakaya, HI et al. Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity. (2015). Currently, the most effective method to prevent influenza is vaccination with a seasonal trivalent or quadrivalent vaccine containing antigens of H1N1, H3N2, and one or two… Read more »

Renowned glycobiologist and influenza researcher, Dr. Richard Cummings, moves to Harvard Medical School

Dr. Richard Cummings, an investigator with the Emory-UGA Centers of Excellence for Influenza Research and Surveillance (CEIRS), recently joined Harvard Medical School and Beth Israel Deaconess Medical Center. The CEIRS DPCC staff took this opportunity to talk to Dr. Cummings about his research on glycobiology and influenza. Dr. Richard Cummings, one of the foremost experts… Read more »

Neutrophil trails are essential for guiding T cells to the site of influenza infection

NIAID CEIRS | Research Publication Commentary Lim, K., et al. Neutrophil trails guide influenza-specific CD8+ T cells in the airways. Science. (2015). A well-functioning immune system is critical for protection against infection, and requires coordination of both the innate and adaptive immune response. The innate immune response, usually the first line of defense, consists of… Read more »

New Vaccine Backbone Increases Vaccine Production in Mammalian Cells

NIAID CEIRS | Research Publication Commentary Ping, J., et al. Development of high-yield influenza A virus vaccine viruses. Nat Communications (2015). The majority of influenza vaccines, including most annual seasonal vaccines and stockpiled vaccines against strains with pandemic potential, are produced in chicken eggs. These egg-based vaccines depend on a large supply of eggs, are… Read more »

Dr. Hualan Chen receives the 2016 L’Oréal-UNESCO For Women in Science Award

The CEIRS Network congratulates Dr. Hualan Chen, who has been named the Asia/Pacific laureate of the 2016 L’Oréal-UNESCO For Women in Science Awards. Dr. Chen is a professor at the Harbin Veterinary Research Institute in China, a part of the Emory-UGA Centers of Excellence for Influenza Research and Surveillance (CEIRS). She is recognized “For her… Read more »

8th Annual CEIRS Network Meeting, July 26-29, 2015

The 8th Annual Centers of Excellence for Influenza Research and Surveillance (CEIRS) Network Meeting was hosted by the New York Influenza Center of Excellence (NYICE) at the University of Rochester in Rochester, NY. More than 270 CEIRS members attended the four-day meeting to discuss accomplishments and contributions of the CEIRS Network in the past year…. Read more »

CEIRS Researchers Recognized for their Scientific Contributions

Several researchers from across the CEIRS Network have recently been recognized for their contributions to the fields of influenza research and virology. The recognitions and awards come from around the globe, showing the true international scope of the CEIRS initiative. The CEIRS Network would like to congratulate our researchers for their outstanding accomplishments. Drs. Stacey… Read more »

Different Gene Activation in Response to Highly Pathogenic Avian Influenza May Explain the High Mortality Rate in Chickens, While Ducks Survive

NIAID CEIRS | Research Publication Commentary Smith, J. et al. A comparative analysis of host responses to avian influenza infection in ducks and chickens highlights a role for the interferon-induced transmembrane proteins in viral resistance. BMC Genomics (2015). The recent highly pathogenic avian influenza (HPAI) H5 outbreak continues to have significant economic impacts on the… Read more »